Acanthamoeba Keratitis Studies
UCSF and Aravind Eye Hospitals in India are investigating the diagnosis and treatment strategies for Acanthamoeba keratitis, a rare but serious cause of corneal blindness.
First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial
A multicenter trial comparing methotrexate and mycophenolate mofetil as first-line immunosuppressive therapies for noninfectious uveitis.
Glaucoma Screening Project
Compares the sensitivity and specificity of portable tests for glaucoma screening at Narayana Nethralaya in Bangalore, India.
PI: UCSF + Narayana Nethralaya
Mycotic Ulcer Treatment Trials (MUTT I & II)
Evaluates natamycin versus voriconazole and oral antifungal use in severe fungal keratitis. Conducted in India and Nepal.
PI: Lietman, Aravind, Dartmouth
Nepal Elimination of Trachoma Study (NETS)
Randomized trial to evaluate mass antibiotic strategies for elimination of ocular chlamydia at the district level in Nepal.
PI: Thomas Lietman, MD
Steroids and Cross-linking for Ulcer Treatment (SCUT II)
Evaluates visual outcomes of antimicrobial treatment alone vs. in combination with collagen cross-linking in India and the U.S.
Systemic and Topical Antiviral Control of Cytomegalovirus Anterior uveitis: Treatment Outcomes (STACCATO)
Two international randomized trials to determine the best treatment and prevention strategy for CMV anterior uveitis.
Telemedicine for CMV Retinitis
In collaboration with Chiang Mai University, this study tests AI-assisted smartphone imaging for CMV diagnosis in HIV+ patients in Thailand.
PI: UCSF + Chiang Mai University
Village Integrated Eye Worker Trial (VIEW I & II)
Assesses community health worker-based eye screening and treatment for corneal abrasions, glaucoma, and AMD in Nepal.