Adalimumab in Juvenile Idiopathic Arthritis-associated Uveitis Stopping Trial (ADJUST)

A randomized, controlled trial evaluating the feasibility of discontinuing adalimumab in patients with quiescent JIA-associated uveitis.

PI: Nisha Acharya, MD, MS

For more please visit: Link

Comprehensive Analysis of Pathogens, Resistomes, and Inflammatory-markers in the CORNea (CapriCORN)

This study identifies pathogens and provides regional AMR profiles to improve diagnostics and treatment for infectious keratitis.

PI: Thuy Doan, MD PhD

For more please visit: Link

Use of Serosurveillance to Support the Trachoma Elimination Endgame

This NIH-funded study uses antibodies in blood to track Chlamydia trachomatis transmission among children globally, supporting trachoma elimination through WHO guidelines.

PI: Benjamin Arnold, PhD

For more please visit: Link

Leveraging Ocular Tissues in Uveitis Study (LOTUS)

A global initiative applying high-throughput sequencing to improve classification, diagnosis, and biomarker discovery for infectious uveitis.

PI: Jessica Shantha, MD

For more please visit: Link

Ocular Rosacea microBiome Study (ORBS)

A randomized clinical trial exploring dosing strategies of doxycycline to improve treatment of symptomatic ocular rosacea.

PI: Gerami Seitzman, MD

For more please visit: Link

Remote Dry Eye Feasibility Study

Explores remote participation in dry eye research using at-home surveys and self-administered tear collection kits.

PI: Gerami Seitzman, MD

For more please visit: Link

SCORPIO

An international study on seasonal conjunctivitis outbreaks, using genomics to identify pathogens and immune responses across sites.

PI: Thuy Doan, MD PhD

For more please visit: Link

Steroids and Cross-linking for Ulcer Treatment (SCUT II)

Evaluates CXL vs. antimicrobial treatments in a multi-site bacterial keratitis trial including India and the U.S.

PI: Thomas M. Lietman, MD

For more please visit: Link

Trachoma Laboratory Surveillance & Diagnostics

The Proctor Foundation lab collaborates to design and optimize molecular assays supporting trachoma eradication strategies across endemic regions.

PI: Proctor Foundation Laboratory Team

Village Integrated Eye Worker (VIEW) Trial I & II

Cluster-randomized trials testing the effectiveness of early intervention and diagnostic screening by trained community health volunteers to reduce corneal ulceration and visual impairment in rural areas.

PI: Thomas M. Lietman, MD & Jeremy Keenan, MD, MPH

For more please visit: Trial I, Trial II